
Uncover the spatial biology dimension with confidence
Although in situ RNA detection techniques (ISH and FISH) have been around for years, they are largely ineffective. They lack robustness and sensitivity to reliably detect the expression of most human genes. Microarray and PCR are gold standard molecular methods for disease profiling, but clinically relevant information regarding cellular and tissue context, as well as spatial variation of the expression patterns, is lost in the process.
Inspired to solve these challenges, scientists at Advanced Cell Diagnostics, a Bio-Techne brand, revolutionized the RNA in situ hybridization method and in 2011 introduced RNAscope ISH for detection of target RNA within intact cells.
Explore Spatial Biology solutions: https://lifescience.invitro.com.au/applications-and-techniques/spatial-biology/