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In a new breakthrough publication, researchers from UT Southwestern Medical Center Texas have generated bovine blastocyst-like structures in vitro using CelVivo’s ClinoStar System. This provides an accessible in vitro blastoid model for studying bovine embryogenesis.

Key Findings:
- The bovine blastoids closely resemble blastocysts in their morphology, cell composition and single-cell transcriptomes.
- Blastoid constructs were achieved by co-culturing bovine blastocyst-derived and trophoblast stem cells.
- Newly identified growth conditions support the derivation and long-term culture of the trophoblast stem cells (3D assembly and culture in suspension).

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