A defined matrix for the growth and differentiation of stem cells and progenitor cells.
Key Benefits
- Reduces experimental variation versus undefined alternatives
- Higher lot-to-lot consistency versus cellular extract preparations
- Quick and simple coating procedure
Why is it important to use a defined culture matrix?
A critical concern when using long-term cell culture protocols is minimizing the amount of introduced experimental variability.
Many researchers plate a variety of cell types using solubilized basement membrane extracts (BME) from the Engelbreth-Holm-Swarm (EHS) mouse sarcoma. These preparations are known to include an undetermined number of extracellular matrix proteins and growth factors. To provide a more defined alternative, R&D Systems optimized a proprietary mixture of recombinant human adhesion molecules specifically for the culture of stem cells and progenitor cells.
StemXVivo® Culture Matrix:
- Reduces experimental variation versus undefined alternatives.
- Has greater lot-to-lot consistency versus cellular extract preparations.
- Is specifically designed for stem cell research.
- Supports growth of TE03, CyT49s, and BG01V human embryonic stem cells, iPS2 human induced pluripotent stem cells, rat cortical stem cells, and mesenchymal stem cells.
- Requires a quick and simple coating procedure.
- Provides a defined alternative to EHS-BME in feeder-free stem cell culture.