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Breast Cancer p53 Hotspot Mutation Cell Line Panel Item ID: ATCTCP2010

Permits and Restrictions

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Organism Homo sapiens, human
Components MDA-MB-175-VII, ATCC HTB-25 MDA-MB-361, ATCC HTB-27 AU565, ATCC CRL-2351 SK-BR-3, ATCC HTB-30 HCC70, ATCC CRL-2315 BT-549, ATCC HTB-122 HCC38, ATCC CRL-2314 MDA-MB-468, ATCC HTB-132
Applications Biological understanding of top genetic alterations across tumor types Novel anti-cancer drug targeting Reactivation of mutant p53 Studies related to p53 molecular mechanisms Testing small molecules or biologics for cancer drug development
Type Strain no
Biosafety Level 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Comments The Breast Cancer p53 Hotspot Mutation Cell Panel is comprised of 8 select cell lines derived from breast cancer that have been sequenced and validated by ATCC. The panel includes both WT p53 cell lines as well as cultures with p53 hotspot mutations at codons 175, 248, 249, or 273.
Product Format frozen
Storage Conditions LN vapor (less than -130°C) only
Permits

These permits may be required for shipping this product to Australia:

  • License agreement required for commercial customer uses.
  • DAFF Import Permit formerly known as AQIS Import Permit must be obtained and a copy of the permit must be sent to ATCC in advance of shipment.
Basic Documentation Product Sheet Certificate of Analysis SDS
Other Documentation p53 Hotspot Mutation Data
Restrictions

Unless the Purchaser has a separate license agreement with The University of Texas M. D. Anderson Cancer Center (“Institution”), the ATCC Material is subject to the following restrictions:

  1. The ATCC Material (and any Modifications, Unmodified Derivatives and/or Progeny thereof) may not be used (1) for commercial purposes or Commercial Use by any Purchaser, or (2) by for-profit or commercial entities for any purpose, provided, however, that ATCC Material that is purchased from ATCC as deoxyribonucleic acid and/or ribonucleic acid or nucleotide chains of any length (hereinafter, “Nucleic Acids”) may be used for internal research purposes by any Purchaser of Nucleic Acids;
  2. Purchaser may not transfer ATCC Materials, Modifications, Unmodified Derivatives, or Progeny to any for-profit entity or commercial entity; and
  3. Purchaser may not use ATCC Materials (or any Modifications, Unmodified Derivatives and/or Progeny thereof) in connection with any research, collaboration or other activities involving a third party that is a commercial entity or for-profit entity.
    4.

The restrictions set forth above are in addition to the restrictions set forth in the ATCC Material Transfer Agreement. Capitalized terms have the meanings set forth in the ATCC Material Transfer Agreement unless otherwise indicated above.

For instructions on how to obtain a license from Institution, please contact Dustin J. Romine, M.A. at the Institution Office of Technology Commercialization via email at dromine@mdanderson.org.

Purchaser acknowledges and agrees that ATCC will send Purchaser’s contact information and order details to Institution’s Office of Technology Commercialization.

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P: 1300 552 003