Permits and Restrictions |
View Permits |
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Organism | Homo sapiens, human |
Components | HOS, ATCC CRL-1543 A-673, ATCC CRL-1598 SK-PN-DW, ATCC CRL-2139 U-2 OS, ATCC HTB-96 Saos-2, ATCC HTB-85 |
Applications | Biological understanding of top genetic alterations across tumor types Validation and characterization of potential cancer driver genes Functional profiling and molecular profiling of subtype-specific cancer cell lines Testing small molecules or biologics for cancer drug development |
Type Strain | no |
Biosafety Level |
1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
Comments | A panel of 5 bone cancer cell lines with varying degrees of genetic complexity. Four lines contain genomic mutations in one or more of the following genes according to the Sanger COSMIC database: CDKN2A, BRAF, TP53, RB1, and PTEN. One cell line without coding mutations serves as a control. |
Product Format | frozen |
Storage Conditions | LN vapor (less than -130°C) only |
Permits |
These permits may be required for shipping this product to Australia:
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Basic Documentation | Product Sheet Certificate of Analysis SDS |
Other Documentation | Cancer cell line mutation data |