CEACAM8/CD66b Antibody (80H3) Summary
| Immunogen |
CML leucocytes |
| Specificity |
NB100-64916 reacts with the CGM6 gene product of the carcinoembryonic gene family. This is a 95-100kD GPI anchored molecule. CEACAM8 is expressed strongly by mature granulocytes and metamyelocytes but weakly by bone marrow myelocytes. CEACAM8 is not expressed by peripheral blood monocytes or lymphocytes. |
| Isotype |
IgG1 |
| Clonality |
Monoclonal |
| Host |
Mouse |
| Gene |
CEACAM8 |
| Purity |
Protein A purified |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.Learn about the Innovator's Reward
|
Applications/Dilutions
| Dilutions |
- Western Blot 1:100-1:2000
- Flow Cytometry 1:50-1:100
- Immunohistochemistry 1:10-1:500
- Immunohistochemistry-Frozen 1:25-1:100
|
| Application Notes |
The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. The use of acetone fixation for frozen sections is recommended. This product contains sodium azide, removal by dialysis is recommended prior to use in functional assays. |
| Publications |
| Read Publication using NB100-64916. |
|
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Buffer |
PBS containing 0.5% BSA |
| Preservative |
0.09% Sodium Azide |
| Concentration |
1.0 mg/ml |
| Purity |
Protein A purified |
Alternate Names for CEACAM8/CD66b Antibody (80H3)
- Carcinoembryonic antigen CGM6
- carcinoembryonic antigen gene family member 6
- carcinoembryonic antigen-related cell adhesion molecule 8
- CD66b antigen
- CD66b
- CD67 antigen
- CD67
- CEACAM8
- CEACAM-8
- CGM6
- NCA-95
- Non-specific cross-reacting antigen NCA-95
Background
CEACAM8 is expressed in leukocytes of Chronic Myeloid Leukemia patients and bone marrow. It belongs to the immunoglobulin superfamily, CEA family. The antigen is expressed strongly by mature granulocytes and meta myelocytes, but only weakly by bone marrow myelocytes. Peripheral blood monocytes and lymphocytes do not express significant amounts of the antigen.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Publications for CEACAM8/CD66b Antibody (NB100-64916)(1)
We have publications tested in 1 confirmed species: Human.
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1 of 1.
| Publication using NB100-64916 |
Applications |
Species |
|---|
| Wong KHK, Tessier SN, Miyamoto DT et al. Whole blood stabilization for the microfluidic isolation and molecular characterization of circulating tumor cells Nat Commun. 2017 Nov 23 [PMID: 29170510] (Human) |
|
Human |
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Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Western Blot
- Immunohistochemistry-Frozen
- Flow Cytometry
- View all Protocols, Troubleshooting, Illustrated assays and Webinars.
Video Protocols
WB Video Protocol
FAQs for CEACAM8/CD66b Antibody (NB100-64916). (Showing 1 - 1 of 1 FAQ).
-
What is the average recovery rate for labeling biotin molecules to a purified antibody?
- The average recovery rate for labeling biotin molecules to any purified antibody is above 75%
Secondary Antibodies
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Isotype Controls
- Mouse Isotype Controls
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- View all of our Isotype Control Products
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Additional CEACAM8/CD66b Products
CEACAM8/CD66b NB100-64916
- CEACAM8/CD66b Antibodies
- CEACAM8/CD66b Lysate
- CEACAM8/CD66b Protein
- CEACAM8/CD66b Proteins and Enzyme
Bioinformatics Tool for CEACAM8/CD66b Antibody (NB100-64916)
Discover related pathways, diseases and genes to CEACAM8/CD66b Antibody (NB100-64916). Need help?
Read the Bioinformatics Tool Guide for instructions on using this tool.
Diseases for CEACAM8/CD66b Antibody (NB100-64916)
Discover more about diseases related to CEACAM8/CD66b Antibody (NB100-64916).
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Pathways for CEACAM8/CD66b Antibody (NB100-64916)
View related products by pathway.
- Neutrophil Activation
- Cell Adhesion
- Localization
- Inflammatory Response
- Phagocytosis
- Respiratory Burst
- Secretion
- Cell Activation
- Immune Response
- Exocytosis
- Leukocyte Activation
- Chemotaxis
- Cell Differentiation
- Cytolysis
- Granulocyte Activation
- Angiogenesis
- Neutrophil Degranulation
- Regulation Of Gene Expression
- Cell Cycle Arrest
- Leukocyte Migration
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PTMs for CEACAM8/CD66b Antibody (NB100-64916)
Learn more about PTMs related to CEACAM8/CD66b Antibody (NB100-64916).
- Phosphorylation
- Glycosylation
- Gpi Anchoring
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Blogs on CEACAM8/CD66b
There are no specific blogs for CEACAM8/CD66b, but you can read our latest blog posts.
