Infors Spinfilter for Labfors 5 - for perfusion processes Item ID: INF72956

As an option, INFORS HT cell for perfusion processes can be equipped with a spin filter. The purpose of the spin filter in continuous perfusion processes is cell-free removal (harvesting) of culture supernatants from bioreactors. Spin filters are in common use in industrial research and development and for production purposes.
The INFORS HT spin filter is used inside the and allows cells to be cultivated permanently under optimal conditions such that there is no need to remove the cell culture from the bioreactor. The fine pores or mesh of the spin filter separate(s) the culture medium gently from the cells. The cell-free culture supernatant is collected in the hollow space of the spin filter and can be removed from the in steps or continuously through an additional harvesting tube. For this purpose, we recommend the use of the precise level control feature through weighing machines or sensors to ensure optimal regulation of the removal/addition of medium.
The use of spin filters is well-suited, in particular, for sensitive cells since it is associated with no changes in the cultivation parameters, such as, e.g., temperature differences from external applications, and there is no adverse influence of external pumps on the cells.
The use of spin filters is well-suited, in particular, for sensitive cells since it is associated with no changes in the cultivation parameters, such as, e.g., temperature differences from external applications, and there is no adverse influence of external pumps on the cells.
The use of INFORS HT spin filters directly in the bioreactor provides additional protection from contamination since the spin filter is integrated in the device and the preparations for the bioprocess are simple.
The spin filter is available in different sizes and pore diameters to suit the requirements of your application.