Infors Bioreactors
Bench-Top Bioreactors
Infors Minifors 2
The award-winning complete bioreactor package. The new standard among bioreactors.
The Minifors 2 is a compact and easy-to-use bioreactor with a full range of application possibilities. It is a complete package that enables both, beginners and experienced users to easily perform applications.
Features
- Available in total volumes of 1.5 L, 3 L and 6 L
- Quick and easy change between culture vessel sizes
- Rounded flat vessel bottom: Low minimum working volume, good mixing, stability with or without a vessel holder
- Safe sampling without any dead volume: INFORS HT Super Safe Sampler
- Intelligent design for easy access to all ports
- Sufficient ports, for standard fittings and extra inlets, immersion tubes and sensors
- 4 x 7.5 mm: addition ports available for acid, base, feed & 1 free
- 4 x 10 mm: sparger, anti-foam system, temperature sensor, sampling/harvest
- Maximum 7 x 12 mm (Pg13.5): pH, pO2, exhaust gas cooler, inoculation are pre-allocated, 3 are freely available
- Convenient, tool-free cleaning and maintenance thanks to knurled screws
- 4 High-performance pumps
- Configurable operating mode: digital (fixed-speed) or analogue (variable speed)
- 3 x fix (acid, base, antifoam), 1 x variable (feed)
- Autoclavable pump heads
- Gravimetric feeding with dosing mode (requires external scale)
- Profile-based pump-speed control (with eve®)
- 2 analogue inputs / outputs to connect external pumps (version for cell cultures)
- 2 integrated MFC for air, air/O2, or air/N2 (version for microorganisms)
- 5 integrated MFC for air, O2, N2, CO2 and head space gassing (version for cell cultures)
- Integrated pressure sensor for detecting a blocked filter
- Gassing optimised for bacteria applications and cell cultures: specific gassing rate (vvm) up to 2.0 min-1
- Multiple cascades for pO2 control by means of stirrer speed, gassing rate (“TotalFlow”) and/or gas composition (“GasMix”)
- Robust, digital connection of pH and pO2 sensors
- Optical pO2 sensor: immediately ready for use, no polarization required
- Calibration data stored in sensor head
- Product calibration of the pH sensor for reliable measurements during long-running bioprocesses
- Optional: biomass sensors from Optek and aquila biolabs
- Integrated 7" touch screen (17.8 cm)
- Simple handling through intuitive menus and practical on-screen help
- Calibration of pH, pO2 and OD sensors using simple install wizards
- Direct data export to USB drive in stand-alone operation
- Multiple display languages
- Planning, controlling and analysing bioprocesses
- Integrated workflows, devices and bioprocess knowledge
- Integrates bioreactors and analytical instruments, regardless of the manufacturer
- Web-based project organisation
- Communication using the latest OPC UA (Minifors 2) or OPC XML-DA standard (Multifors 2, Labfors 5, Techfors-S, Techfors)
- Synchronisation of process-related events such as sampling or inoculation
Technical details
|
Vessels |
1.5 L / 3 L / 6 L |
|
Working volume |
0.3–1.0 L / 0.6–2.0 L / 1.1–4.0 L |
|
Dimensions (W x D x H) |
455 mm x 375 mm x 740 mm |
|
Drive |
Version for Microorganisms: 150 min-1 to 1600 min-1 Version for cell cultures: 24 min–1 to 600 min-1 |
|
Temperature |
+ 15 °C (Coolant temperature + 5 °C) to 60 °C |
|
Gassing per vessel |
Version for microorganisms: 2 MFCs up to 2 min-1, version for cell cultures: 5 MFCs up to 0.15 min-1 |
|
Pumps per vessel |
4 x configurable (fixed or variable speed) ex-works: 3 x fixed (acid, base, anti-foam), 1 x variable (feed) |
|
Pump performance |
0.0034 to 3,52 mL min-1 (standard), 0.017 to 16,13 mL min-1, 0.0012 to 1.12 mL min-1 |
|
Ports per vessel |
7,5 mm 4x |
|
Connectivity |
OPC UA via Ethernet |
|
Parallel operation via touch screen controller |
1 unit |
|
Sterilisation |
Autoclave |
Data Sheets
Flyer & Brochures
Application Notes
Biological and process-engineering characterization of the Minifors 2 laboratory bioreactor
Download App Note
Process transfer of CHO cultivations using the Minifors 2 as an example
Download App Note
White Papers
Infors Multifors 2
Parallel bioreactor for bioprocess development.
Parallel bioreactor system for small-scale bioprocesses.
With Multifors 2 you can work with up to six bioprocesses in parallel. Thanks to a selection of preconfigured packages and a variety of connection possibilities and options, you will be ideally equipped for optimizing sophisticated bioprocesses on a small scale.
Features
- Basic setup includes four precision pumps per culture vessel (option of one more)
- Autoclavable pump heads
- Gravimetric feeding (with external scale)
- Profile-based pump-speed control with eve®
- Culture vessels are easy to exchange
- Powerful magnetic drive
- Magnetic coupling reduces the risk of contamination and simplifies handling
- Motor underneath the vessel for excellent accessibility to available ports
- Up to 13 ports for sensors (antifoam, optical density, pH, pO2, redox, conductivity, live cell density, etc.)
- Customer-specific gassing with up to 5 gas lines
- Feed via rotameter or mass-flow regulator
- Cascades may be configured in serial or in parallel for controlling the pO2 via the stirrer speed, gassing rate, gas composition, etc.
- Customers may choose from digital (Modbus) or analog sensors.
- Product calibration of the pH sensor for reliable measurements during long-running bioprocesses
- If required, additional sensors and actuators can be connected.
- Touchscreen with integrated OPC server
- Reliable measurement and setting of the bioprocess parameters and communication with eve®
- Parallel management and control of up to six devices
- Up to 24 selectable parameters, such as temperature, stirring speed, pH, pO2, anti-foaming agent, feed
- Planning, controlling and analysing bioprocesses
- Integrated workflows, devices and bioprocess knowledge
- Integrates bioreactors and analytical instruments, regardless of the manufacturer
- Web-based project organisation
- Communication using the latest OPC UA (Minifors 2) or OPC XML-DA standard (Multifors 2, Labfors 5, Techfors-S, Techfors)
- Synchronisation of process-related events such as sampling or inoculation
Technical Details
|
Vessels |
0,4 L / 0,75 L / 1,4 L |
|
Working volume |
0,15–0,25 L / 0,18–0,5 L / 0,32–1 L |
|
Dimensions (W x D x H) |
350 mm x 520 mm x 960 mm |
|
Drive |
Magnetic drive to 1600 min-1 |
|
Temperature |
Coolant temperature + 5 °C to 70 °C |
|
Gassing per vessel |
Up to 4 rotameters oder MFCs up to 2 min-1 (vvm) |
|
Pumps per vessel |
3 fixed, 1 variable, optional 1 additional variable |
|
Pump performance |
Depending on the design from 0,0012 mL min-1 to 3,46 mL min-1 |
|
Ports per vessel |
7 mm 4x |
|
Connectivity |
OPC XML DA via Ethernet |
|
Parallel operation via touch screen controller |
3 base units, resp. 6 vessels |
|
Sterilisation |
Autoclave |
Infors Labfors 5
High-end bench-top bioreactor for all applications.
A truly universal bioreactor.
The Labfors 5 is suitable for microorganisms, phototrophic organisms as well as solid subtrates and enzymatic bioprocesses. There are almost no limits to its uses.
Features
- Working volumes ranging between 0.5 and 10 L
- Can be configured according to individual needs thanks to a selection of different stirrers, spargers and specialized accessories
- Up to 14 ports for sensors (antifoam, optical density, pH, pO2, redox, conductivity, live cell density, etc.)
- No welded lid components—ideal for GMP applications
- Basic setup includes four precision pumps per culture vessel (option of one more)
- Autoclavable pump heads
- Gravimetric feeding (with external scale)
- Profile-based pump-speed control with eve®
- Customer-specific gassing with up to 5 gas lines
- Feed via rotameter or mass-flow regulator
- Cascades may be configured in serial or in parallel for controlling the pO2 via the stirrer speed, gassing rate, gas composition, etc.
- Customers may choose from digital (Modbus) or analog sensors.
- Product calibration of the pH sensor for reliable measurements during long-running bioprocesses
- If required, additional sensors and actuators can be connected.
- Touchscreen with integrated OPC server
- Reliable measurement and setting of the bioprocess parameters and communication with eve®
- Parallel management and control of up to six devices
- Up to 24 selectable parameters, such as temperature, stirring speed, pH, pO2, anti-foaming agent, feed
- Planning, controlling and analysing bioprocesses
- Integrated workflows, devices and bioprocess knowledge
- Integrates bioreactors and analytical instruments, regardless of the manufacturer
- Web-based project organisation
- Communication using the latest OPC UA (Minifors 2) or OPC XML-DA standard (Multifors 2, Labfors 5, Techfors-S, Techfors)
- Synchronisation of process-related events such as sampling or inoculation
Technical Details
|
Vessels |
2 L / 3,6 L / 7,5 L / 13 L |
|
Working volume |
0,5–1,2 L / 0,5–2,3 L / 1–5 L / 2,2–10 L |
|
Dimensions (W x D x H) |
464 mm x 462 mm x 996 mm |
|
Drive |
Direct drive up to 1500 min–1 |
|
Temperature |
Coolant temperature + 5 °C bis 70 °C |
|
Gassing per vessel |
Up to 5 rotameters or MFCs up to 2 min-1 (vvm) |
|
Pumps per vessel |
3 fixed, 1 variable, optional 1 additional variable 3 |
|
Pump performance |
Depending on version, from 1,2 μl min–1 to 17,1 ml min–1 |
|
Ports per vessel |
7 mm max. 4x |
|
Connectivity |
OPC XML DA via Ethernet |
|
Parallel operation via touch screen controller |
up to 6 vessels |
|
Sterilisation |
Autoclave or LabCIP (microbial version) |
Data Sheets
Data Sheet - Labfors 5 Version for Microorganisms
Data Sheet - Labfors 5 Version for Solid Substrates and Enzymatic Bioprocesses
Flyer & Brochures
LabCIP - Automatic Cleaning and Sterilization at the Push of a Button
Practical Advice
The Cookbook - A Guide for Biotech Beginners
Download PDF
White Paper
Continuous Culture as the Universal Bioprocess for Manufacturing
Pilot Bioreactors
Infors Techfors-S
Compact in-situ sterilizable bioreactor.
In situ bioreactors made easy.
Is the first step always the hardest? Not with the Techfors-S. The Techfors-S contains exactly the same components as our bench bioreactors. This ranges from the pumps via the gassing line to the touch screen controller and the associated software. Both beginners as well as process experts will be able to manage easily.
Features
- Working volume from 3 to 30 l
- Double jacket made of 316L stainless steel
- Individually configurable with a selection of different impellers, spargers and special accessories
- Up to 14 ports for sensors (anti-foam, optical density, pH, pO2, redox, conductivity, live cell density, etc.)
- 1 port in the bottom of the vessel for harvesting/sampling
- Basic setup includes four easy-load precision pumps per culture vessel (option of two more)
- Gravimetric feeding (with external scale)
- Profile-based pump-speed control with eve®
- Customer-specific gassing with up to 5 gas lines
- Feed via rotameter or mass-flow regulator
- Cascades may be configured in serial or in parallel for controlling the pO2 via the stirrer speed, gassing rate, gas composition, etc
- Customers may choose from digital (Modbus) or analog sensors.
- Product calibration of the pH sensor for reliable measurements during long-running bioprocesses
- If required, additional sensors and actuators can be connected.
- Touchscreen with integrated OPC server
- Reliable measurement and setting of the bioprocess parameters and communication with eve®
- Up to 24 selectable parameters, such as temperature, stirring speed, pH, pO2, anti-foaming agent, feed
- Planning, controlling and analysing bioprocesses
- Integrated workflows, devices and bioprocess knowledge
- Integrates bioreactors and analytical instruments, regardless of the manufacturer
- Web-based project organisation
- Communication using the latest OPC UA (Minifors 2) or OPC XML-DA standard (Multifors 2, Labfors 5, Techfors-S, Techfors)
- Synchronisation of process-related events such as sampling or inoculation
Technical Details
|
Vessels |
15 l / 30 l / 42 l |
|
Working volume |
3–10 l / 5,3 l–20 l / 6–30 l |
|
Dimensions (W x D x H) |
1017 mm x 934 mm x 1841 mm |
|
Drive |
Direct drive to 1200 min-1 |
|
Temperature |
Coolant temperature + 5 °C to 79 °C; to 125 °C for sterilisation |
|
Gassing per vessel |
up to 4 MFCs |
|
Pumps per vessel |
4 fixed, optional 2 additional variable |
|
Ports per vessel |
Top plate: Vessel bottom: |
|
Connectivity |
OPC XML DA via Ethernet |
|
Parallel operation via touch screen controller |
- |
|
Sterilisation |
Sterilisation-in-Place |
Infors Techfors
Pilot bioreactor for bioprocess professionals.
Pilot bioreactor for sophisticated bioprocesses.
There are practically no limits on flexibility with regard to design and operation, since each pilot bioreactor model is built individually according to your needs. You specify the requirements – we implement them after performing a thorough feasibility study.
Features
- Working volume up to 660 L
- Double jacket made of 316L stainless steel
- Optionally with single or double mechanical seal
- Individually configurable with a selection of different impellers, spargers and special accessories
- Individually configurable no. ports for sensors (anti-foam, optical density, pH, pO2, redox, conductivity, live cell density, etc.)
- Pivoting vessel lid for easy access as an option
- Easy movement of the device possible with stable wheels (up to approx. 300 L)
- Basic setup includes four easy-load precision pumps per culture vessel (option of two more)
- Gravimetric feeding (with external scale)
- Profile-based pump-speed control with eve®
- Customer-specific gassing via rotameter or mass-flow regulator
- Cascades may be configured in serial or in parallel for controlling the pO2 via the stirrer speed, gassing rate, gas composition and pressure
- Can be extended at any time
- Customers may choose from digital (Modbus) or analog sensors.
- Product calibration of the pH sensor for reliable measurements during long-running bioprocesses
- If required, additional sensors and actuators can be connected.
- FDA compliance is taken into account
- Based on GMP standards
- Qualification options: IQ/OQ/FAT/SAT
- Planning, controlling and analysing bioprocesses
- Integrated workflows, devices and bioprocess knowledge
- Integrates bioreactors and analytical instruments, regardless of the manufacturer
- Web-based project organisation
- Communication using the latest OPC UA (Minifors 2) or OPC XML-DA standard (Multifors 2, Labfors 5, Techfors-S, Techfors)
- Synchronisation of process-related events such as sampling or inoculation
Technical Details
|
Vessels |
up to 1000 L |
|
Working volume |
up to 660 L |
|
Dimensions (W x D x H) |
Depending on specification |
|
Drive |
Depending on specification |
|
Temperature |
up to 79 °C for temperature control; up to 125 °C for sterilisation |
|
Gassing per vessel |
Depending on specification |
|
Pumps per vessel |
3 fixed, 1 variable, optional 2 additional |
|
Ports per vessel |
Depending on specification |
|
Connectivity |
OPC XML DA via Ethernet |
|
Parallel operation via touch screen controller |
1 base unit |
|
Sterilisation |
Sterilisation-in-Place |