Cytokines & Growth Factors
Together with our partner, Bio-Techne, we offer a wide selection of R&D Systems® and Novus Biologicals bioactive recombinant proteins for multiple species. Our portfolio includes cytokines and growth factors, proteins for studying immuno-oncology targets, enzymes, Animal-Free™ and GMP-grade proteins, custom protein development services, and more.
Quality is our number one priority. Bio-Techne manufacture more than 95% of our proteins at their facility. This means we have complete control over all quality testing and nothing becomes a product that does not meet the industry-leading specifications.
Introducing AI Modified Proteins
Explore the benefits of culturing your T cells or tumor-infiltrating lymphocytes (TILs) with the new IL-2 Heat Stable Agonist Protein. Engineered using artificial intelligence (AI), this protein has enhanced stability, enabling it to withstand high temperatures and extended culture durations.
• High Levels of Biological Activity: The biological activity of each protein is tested in an appropriate biological system to confirm that it meets strict QC activity parameters before it is released to market.
• Lot-to-Lot Consistency: Minimal lot-to-lot variability is ensured by maintaining consistent manufacturing conditions and testing each new lot side-by-side with previous lots and with a master lot, so you don’t have to worry whether results will be reproducible over time.
• High Purity: Most of our proteins have >95% purity and a guaranteed industry-leading endotoxin level of <0.1 EU/ug by the LAL method.
• Long-term Stability: The bioactivity and physical state of our proteins are monitored through multiple freeze/thaw cycles, so you can be confident that your protein will be stable over long periods of time. All proteins are shipped lyophilized or in specially optimized formulations to ensure that they reach you in perfect condition.
• Comprehensive Selection: Catalog includes a large selection of biologically active recombinant and natural proteins spanning 35 species, and more than 10,000 non-catalog proteins for multiple different research areas, allowing you to easily find the proteins that you need.
• Multiple Host Expression Systems, Tags, and Labels: Our proteins are produced in a variety of host expression systems and are either untagged or include a biotin, Fc, or His tag, or a fluorescent label to meet different experimental needs.
• Seamless Transition from RUO to GMP: Our Animal-free and GMP-grade proteins frequently originate from the same clone, sequence, and expression system as our traditional research-grade proteins, making the transition from basic research into process development and clinical manufacturing as efficient and seamless as possible.
• Bulk Proteins at Discounted Prices: Bio-Techne has the capacity and the expertise to scale up the production of any protein and we offer economical pricing on bulk orders.
• Custom Protein Capabilities: If you don’t see the protein that you need on the website, we offer custom protein services. From scratch protein development to customizing a protein from the catalog, custom services team will work with you to create the product that fits your experimental needs.
• Custom Bottling Options: If your research requires a special formulation or size, custom bottling options are available.
• Expert Customer Support Assistance: Almost all of our proteins are manufactured in-house at Bio-Techne, allowing us to maintain complete control over the quality of our products. If you have any questions about our products, our protein scientists and highly trained technical service team are always available to assist you.
Featured Products
Cytokines and Growth Factor
- The most reliable source of cytokines and growth factors for immune cell, stem cell, and neural cell culture
- An unparalleled selection of recombinant proteins for studying interleukins, interferons, chemokines, adipokines, and TNF superfamily members
- The highest quality, most consistent cytokines and growth factors for organoid cell culture
- Bulk and custom protein services to meet every researcher’s need
Immune Check Point Proteins
- Proteins for studying common targets including PD-1, PD-L1, and CTLA-4, and emerging targets such as TIGIT, LAG-3, Butyrophilins, and LILR family members
- Multiple tags available including Fc, His, and an expanding selection of Avi-tag biotinylated proteins.
- Proteins for a range of different species including many non-human primate proteins with over 80 cynomolgus and rhesus monkey immune checkpoint proteins
Download Poster for Immune Checkpoint Targets for Cancer Immunotherapy
GMP Proteins
- Extensive documentation for traceability of source
- Rigorous lot-to-lot consistency testing against a master lot
- Additional quality control testing and quality assurance review
Bulk Proteins
- The expertise and ability to scale up the production of almost any protein
- Specialized formulations available
- Economical pricing
Avi-tag and Amine-Labelled Biotinylated Proteins
- Avi-tag biotinylated proteins incorporate a single biotin within the Avi-tag to provide consistent labeling and uniform protein orientation for binding assays
- Amine-labeled biotinylated proteins incorporate multiple biotins per molecule, allowing for high signal strength and binding efficiency
- All R&D Systems™ biotinylated proteins are rigorously tested to ensure that they exhibit the same level of bioactivity as the unlabeled protein and exhibit minimal lot-to-lot variability
