A recent publication on reprogramming fibroblasts into induced pluripotent stem cells using the Seahorse extracellular flux analyser identified that nuclear reprogramming efficiency might be improved by modulating mitochondrial spare capacity. Namely, cells with lower spare respiratory capacity produce iPSCs at higher efficiencies.
Discover how these metabolic measurements can be used as indicators to minimise workflow inefficiencies and improve differentiation and reprogramming approaches.
> View selected Stem Cell research publications citing Agilent Seahorse XF Data
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Cat. No. |
Product Name |
Description |
1254 |
Selective p160ROCK inhibitor; increases survival rate of human embryonic stem cells undergoing cryopreservation |
|
1614 |
Induces proliferation, differentiation and sheet formation of ESC-derived endothelial cells |
|
2634 |
γ-secretase inhibitor; induces neuronal differentiation |
|
4423 |
Highly selective GSK-3 inhibitor; enables reprogramming of mouse embryonic fibroblasts into iPS cells |
|
6053 |
Potent and selective ALK2 and ALK3 inhibitor; promotes neural induction of hPSCs |
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