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Accurate and Reliable detection of DNA Aberrations with new Chromogenic Assay

Current FISH techniques fall short on morphological detail due to utilisation of fluorescent nuclear staining and relying on expensive high-resolution microscopes. Additionally, use of Bacterial Artificial Chromosome (BAC) clone-based probes that are large and tend to span multiple genes, lack single gene detection specificity limiting the scale and development of DNA research.

To overcome these limitations, we are introducing a new chromogenic DNA in situ hybridization (ISH) technology. DNAscope™ employs the proven “double-Z” probe design and signal amplification system of RNAscope™, enabling rapid and flexible probe development for any DNA target enabling visualization of target in paraffin embedded tissues.

Key Advantages

key advantages

duplex assay 1

detection 1