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Caspase-8 Assay Kit Summary

Description Caspase-8 Staining Kit (Red) is used for sensitive detection of activated caspase-8 in living cells with sulfo-rhodamine.
Kit Type Assay Kit
Gene CASP8

Packaging, Storage & Formulations

Storage Store at -20C.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Caspase-8 Assay Kit

  • AIS
  • androgen receptor
  • CASP8
  • Caspase8
  • Caspase-8
  • DHTRTFM
  • Dihydrotestosterone receptorHYSP1
  • HUMARA
  • Mch5
  • NR3C4KD
  • Nuclear receptor subfamily 3 group C member 4
  • SMAX1SBMA
  • spinal and bulbar muscular atrophy

Background

Caspase-8 Staining Kit (Red) is used for sensitive detection of activated caspase-8 in living cells with sulfo-rhodamine.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Kits are guaranteed for 6 months from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
  • Flow Cytometry
  • View all Protocols, Troubleshooting, Illustrated assays and Webinars.

FAQs for Caspase-8 Kit (KA0760). (Showing 1 - 1 of 1 FAQ).

  1. May we ask the MW difference between the active form and the proform of Caspase 8 while performing WB?
    • In treated cells induced to undergo apoptosis, caspase-8 migrates as a 55/53 kDa (pro-form), 41/42 kDa (a cleaved/active or intermediate form), and 18 kDa (active form). The proform (55/53 kDa) is still seen in treated cells because not all cells undergo apoptosis at once.

Additional Caspase-8 Assay Kit Products

Caspase-8 KA0760
  • Caspase-8 Antibodies
  • Caspase-8 ELISA Kits
  • Caspase-8 Kits
  • Caspase-8 Lysates
  • Caspase-8 Proteins

Related Products by Gene

BAX, BCL2, BCL2L1, BID, CASP3, CASP9, CASPASE 3, CASPASE 8, CASPASE 9, CFLAR, CYCS, FADD, FAS, FASLG, PARP1, TNF, TNF-RELATED APOPTOSIS-INDUCING LIGAND, TNFRSF10A, TNFRSF10B, TNFSF10

Bioinformatics Tool for Caspase-8 Kit (KA0760)

Discover related pathways, diseases and genes to Caspase-8 Kit (KA0760). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.

Diseases for Caspase-8 Kit (KA0760)

Discover more about diseases related to Caspase-8 Kit (KA0760).
  • Malignant Neoplasms
  • Neoplasms
  • Carcinoma
  • Leukemia
  • Mammary Neoplasms
  • Malignant Neoplasm Of Breast
  • Malignant Paraganglionic Neoplasm
  • Inflammation
  • Neuroblastoma
  • Lymphoma
  • Malignant Tumor Of Colon
  • Adenocarcinoma
  • Prostatic Neoplasms
  • Liver Carcinoma
  • Colonic Neoplasms
  • Lung Neoplasms
  • Malignant Neoplasm Of Prostate
  • Cell Transformation, Neoplastic
  • Malignant Neoplasm Of Lung
  • Glioma
 

Pathways for Caspase-8 Kit (KA0760)

View related products by pathway.
  • Cell Death
  • Induction Of Apoptosis
  • Cell Cycle
  • Pathogenesis
  • Programmed Cell Death
  • Cell Proliferation
  • Methylation
  • Sensitization
  • Cell Growth
  • Localization
  • Release Of Cytochrome C From Mitochondria
  • Apoptotic Process
  • Proteolysis
  • Cell Cycle Arrest
  • Secretion
  • Immune Response
  • Dna Methylation
  • Cell Killing
  • Dna Repair
  • Rna Interference
  •  

PTMs for Caspase-8 Kit (KA0760)

Learn more about PTMs related to Caspase-8 Kit (KA0760).
  • Cleavage
  • Phosphorylation
  • Methylation
  • Dephosphorylation
  • Demethylation
  • Acetylation
  • Ubiquitination
  • Reduction
  • Oxidation
  • Nitrosylation
  • Biotinylation
  • Myristoylation
  • Ribosylation
  • Sumoylation
  • Phosphorothioation
  • Prenylation
  • Acylation
  • Farnesylation
  • Glycosylation
  • Deacetylation
 

Research Areas for Caspase-8 Kit (KA0760)

Find related products by research area.
  • Apoptosis
  • Cancer
  • Caspases
  • Cell Biology
  • Ubiquitin Proteasome Pathway

Blogs on Caspase-8.

Check out the latest blog posts on Caspase-8.
Caspase 3, the executioner of apoptosisCaspase-3 enzyme is a member of the family of endoproteases which regulate inflammation and apoptosis signaling networks. Caspase-3 is known as an executioner caspase in apoptosis because of its role in coordinating the destruction of cellular stru...  Read full blog post.
VPS41 - An important regulator of lysosomal traffickingMembrane fusion is an essential step during the trafficking of endosomes and vesicles throughout the cell. Membrane fusion events are facilitated by multisubunit tethering complexes (MTC) including CORVET and HOPS. These complexes interact with Rab...  Read full blog post.
Caspase-8 - a pro-apoptotic protein with dynamic roles in normal physiology and pathologyCaspases are a family of cysteine-aspartic acid proteases that are responsible for the initiation and execution of apoptosis. Caspase-8 is a 55 kDa protein expressed as an inactive procaspase that resides in the cytosol. Activation of Caspase-8 req...  Read full blog post.
Caspase 8 - a key mediator of apoptosis Programmed cell death via apoptosis is a key controlled physiological process instigated by the cell death receptor family, their ligands, and the caspase cysteine protease family. All caspases exist in a precursor form that contains a prodomain, a...  Read full blog post.