Leukemia p53 Hotspot Mutation Cell Line Panel Item ID: ATCTCP2070
| Permits and Restrictions |
View Permits |
|---|---|
| Organism | Homo sapiens, human |
| Components | CESS, ATCC TIB-190 HL-60, ATCC CCL-240 CCRF-CEM, ATCC CCL-119 CEM/C1, ATCC CRL-2265 KASUMI-1, ATCC CRL-2724 ARH-77, ATCC CRL-1621 |
| Applications | Biological understanding of top genetic alterations in leukemia Novel anti-cancer drug targeting Reactivation of mutant p53 Studies related to p53 molecular mechanisms Testing small molecules or biologics for cancer drug development |
| Biosafety Level |
2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Comments | The Leukemia p53 Hotspot Mutation Cell Panel is composed of six select suspension cell lines derived from individuals with leukemia. The mutations have been sequenced and validated by ATCC. This panel includes p53 wild type cell lines as well as p53 mutant lines that carry hotspot mutations in one of the following codons: 175, 248 and 273. |
| Product Format | frozen |
| Storage Conditions | liquid nitrogen vapor phase |
| Permits |
These permits may be required for shipping this product to Australia:
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| Basic Documentation | Product Sheet Certificate of Analysis SDS |
| Other Documentation | p53 Hotspot Mutation Data |