Leukemia Cell Line Panel Item ID: ATCTCP1010
| Permits and Restrictions |
View Permits |
|---|---|
| Organism | Homo sapiens, human |
| Components | KASUMI-1, ATCC CRL-2724 HL-60, ATCC CCL-240 THP-1, ATCC TIB-202 K-562, ATCC CCL-243 RS4;11, ATCC CRL-1873 MOLT-4, ATCC CRL-1582 CCRF-CEM, ATCC CCL-119 |
| Disease | leukemia |
| Applications | Biological understanding of top genetic alterations in leukemia Validation and characterization of potential cancer driver genes Functional profiling and molecular profiling of subtype-specific cancer cell lines Testing small molecules or biologics for cancer drug development |
| Type Strain | no |
| Biosafety Level |
1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Comments | A panel of 7 leukemia cell lines representing Acute Myeloid Leukemia (AML), Acute Monocytic Leukemia (AMoL), Chronic Myeloid Leukemia (CML), and Acute Lymphoblastic Leukemia (ALL). Each culture contains genomic mutations in one or more of the following genes according to the Sanger COSMIC database: CDKN2A, KDM6A, TP53, NRAS, NOTCH1, PTEN, FBXW7, FLT3, KRAS, MLH1, and PIK3R1. |
| Product Format | frozen |
| Storage Conditions | LN vapor (less than -130°C) only |
| Permits |
These permits may be required for shipping this product to Australia:
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|---|---|
| Basic Documentation | Product Sheet Certificate of Analysis SDS |
| Other Documentation | Leukemia cell line mutation data |