Permits and Restrictions |
View Permits |
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Organism | Homo sapiens, human |
Components | SNU-C1, ATCC CRL-5972 SW48, ATCC CCL-231 RKO, ATCC CRL-2577 COLO 205, ATCC CCL-222 SW1417, ATCC CCL-238 LS411N, ATCC CRL-2159 NCI-H508, ATCC CCL-253 HT-29, ATCC HTB-38 |
Applications | Biological understanding of top genetic alterations across tumor types Validation and characterization of potential cancer driver genes Functional profiling and molecular profiling of subtype-specific cancer cell lines Testing small molecules or biologics for cancer drug development |
Type Strain | no |
Biosafety Level |
1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
Comments | A panel of 8 colon cancer cell lines with varying degrees of genetic complexity. They have genomic mutations in one or more of the following genes according to the Sanger COSMIC database: BRAF, APC, CTNNB1, EGFR, FBXW7, NF1, PIK3CA, PIK3R1, SMAD4, and TP53. |
Product Format | frozen |
Storage Conditions | LN vapor (less than -130°C) only |
Permits |
These permits may be required for shipping this product to Australia:
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Basic Documentation | Product Sheet Certificate of Analysis SDS |
Other Documentation | Cancer cell line mutation data |